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NCBI Activity: Male Pattern Baldness

Group: Ben Ernest, Joel Bucci, Letitia Olson

Goal: to find more information on male pattern baldness, how chemical imbalances and genetic variations cause hair loss, and potential treatments for this disorder

Introduction: Male pattern baldness has several potential causes including endocrine disorders and genetic mutations, among others. The hair loss is initiated by dysfunction in […]

NCBI : Activity Personal BLAST Database Development ; Dylan Storey


In order to compare previously sequenced RFLP clones and EST clones used in marker development for genetic mapping in pepper to a chip developed by industry a BLAST database of proprietary sequences needs to be compiled. Using the toolkit developed by NCBI I’m in currently in the process of compiling a database of these […]

Promoter Prediction in Genetics

Group: Jianzhuang, Xuejuan and Xiaomin.

Topic: Promoter Prediction in genetics

Introduction: A promoter is a region of DNA that facilitates the transcription of a particular gene. I am interested in this problem because this is one of the most important, difficult and popular topics in the genomics.


Prediction and integration of regulatory and protein-protein […]

NCBI Activity:

Group: Brittany and Randy

Topic: Cyclic AMP

Introduction: Cyclic AMP, a secondary messenger, is invovled in numerous biological processes. We are interested in the research involving brain function and the role cAMP plays. Research is being done on cAMP and its involvement in mood disorders associated in the brain.


Adenylyl cyclase-cyclicAMP signaling in mood […]

NCBI Activity:Canine Parvovirus

Group: Yijia, Xiaoxin, Zhou

Topic: Canine Parvovirus

Intro: Canine parvovirus is a pathogen of dogs that emerged in 1970s. It’s a highly contagious disease that inflicts adult dogs, but mostly concentrates on puppies. The most common syndroms of this disease are depression, loss of appetite, severe diarrhea, and vomiting. Vaccines can prevent this infection, but […]

NCBI Activity 2009: Exploring the stability of Taq Polymerase by Keats Shwab and Jason Harris


We are invstigating a very well used enzyme, Taq polymerase. We wish to understand the structural characteristics which make it ideal for high temperature activity. We we also would like to see how related its peptide sequence is to non thermophillic polymerases.


All DNA polymerases have a similar structure that is related to […]

NCBI Activity: Elizabeth & Dmitriy; Hsp 70

Group: Elizabeth & Dmitriy

Topic: Gene Conversion and GC content in Hsp 70 (Heat Shock Protein)


HSP70 is a highly conserved family of ubiquitous chaperon proteins. This study used several HSP70 proteins with very high similarity in the amino acid sequence but in contrast, great variance in the codons which code for the amino […]

NCBI Activity: CYP12d1

Cytochrome P450s (CYPs) are found in all organisms and metabolize many xenobiotic chemicals organisms come into contact with everyday. CYP12d1 is found in Drosophila and is known to metabolize DDT. Insecticide resistant strains of Drosophila over-express CYP12d1 along with many other CYP genes.

August 5th, 2009 | Category: NCBI | Comments are closed

NCBI Activity: SIZ1

Person: Ayla

Topic: SIZ1 E3 SUMO Ligase

Introduction: The topic of my undergraduate research was overexpressing the E3 SUMO ligase, SIZ1 in turfgrass and rice to improve drought tolerance. The first article by Catala’s lab is the one that was majorly cited in my research project. Many procedures came from it. The article about flowering […]

NCBI Activity: ICAM-1 (Intercellular Adhesion Molecule)

Group: Ellen, Jerreme, Stephen

Introduction: ICAM-1 is a human gene that encodes for a protein, inter-cellular adhesion molecule-1. The ICAM-1 is an immunoglobulin protein expressed on endothelial and antigen presenting cells. The expression of ICAM on endothelial cells can be induced by inflammatory cytokines, which promotes firm adhesion of the leukocytes to the site of […]