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By Xiaomin and Jianzhuang Introduction: Wnt proteins form a family of highly conserved secreted signaling molecules that regulate cell-to-cell interactions during embryogenesis. Wnt proteins bind to receptors of the Frizzled and LRP families on the cell surface. Mutations in Wnt genes or Wnt pathway components lead to specific developmental defects, while various human diseases, including […] Goup: Ben Ernest, Joel Bucci, Letitia Olson Intro: Cytochrome C oxidase is an enzyme in the electron transport chain that catalyzes electron transfer to reduce oxygen to water. This reaction produces protons, which are then used to power the ATP synthases Reference: Axel Harrenga and Hartmut Michel. The Cytochrome c Oxidase from Paracoccus denitrificans Does […] Intro: This particular enzyme is an oxidative enzyme that imparts bioluminescence to the firefly Photinus pyralis. In research, the enzyme is used to study anesthetic-protein interactions. Ref: Structural basis for the inhibition of firefly luciferase by a general anesthetic. Franks, N.P., Jenkins, A., Conti, E., Lieb, W.R., Brick, P. Biophys.J. v75 […] Intro: Gyrase is a protein involved in maintaining the negative supercoiled structure of DNA. It is a two subunit protein and its function in DNA is ATP dependent. Because of its function gyrase is involved in many DNA associated processes including replication, transcription and repair. DNA Gyrase: Structure and Function Reece, R.J.; Maxwell, A Crit […] LHCII- Light Harvesting Complex II is part of photosynthesis in higher plants, algae and some bacteria. It is the primary chlorophyll binding protein, andis associated with both of the Photosystems. LHCII also controls the lamellar structure of the thylakoid membrane. It exists as a trimer its natural state composed of a varying combination of three […] Dylan, Ellen, Stephen, and Jerreme Alcohol Dehydrogenase Alcohol dehydrogenase (ADH) is an enzyme that catalyzes the conversion of alcohols to aldehydes or ketones and a reduction of NAD+ to NADH. ADH is advantageous to humans because it prevents alcohol toxicity by breaking down alcohol. ADH oxidizes only secondary and tertiary alcohols to aldehydes and ketones […] Green Fluorescent Protein (GFP) It’s a protein that glows green when exposed to blue light. It comes from the jellyfish Aequorea victoria. It is often used in experiments as a reporter gene. We chose it because it GLOWS!!! PBD ID: 2g6e Sources: http://www.pdb.org/pdb/explore.do?structureId=2G6E# http://www.pdb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb42_1.html Looked at chain A in jmol Species source Aequoria victoria (jellyfish), […] |
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