Project Module

Posted by on Aug 12 2008 | Blogging

It was once believed that neurons were not able to regenerate. This meant that whenever neurons were destroyed they would not be replaced, leading to neurodegenerative and debilitating diseases like Parkinson and Alzheimer. Recent work in neuroscience has shown that neural stem cells are plentiful in the brain and that they could be activated and made to differentiate into normal functioning neurons, if  proteins ephrin A2 and A3, released by the supporting astrocytes in the area, were removed .Our module seeks to investigate the structural and functional characteristics of ephrin A2 and A3 by comparing them with the structure and functions of closely related  known proteins.  This study should advance our understanding of possible interactions between ephrin A2 and A3 and their receptors with the hope of finding a cure for neurodegenerative diseases.  

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