This project was prepared as part of a BioQUEST faculty development workshop entitled BioQUEST Summer 2008 Faculty Workshop Problem Solving in Biology: Data, Tools and Resources from Plant Science at Southeast Missouri State University in June 2008. The BioQUEST Curriculum Consortium is committed to the reform of undergraduate biology instruction through an emphasis on engaging students in realistic scientific practices. This approach is sometimes characterized as an inquiry driven approach and is captured in BioQUEST's three P's (problem-posing, problem-solving, and peer-persuasion). As part of this workshop groups of faculty were encouraged to initiate innovative curricular projects. We are sharing these works in progress in the hope that they will stimulate further exploration, collaboration and development. Please see the following links for additional information:

Upcoming events               BEDROCK Problem Spaces

MASE: A Model of Mutation and Selection: Evolution
Authors          Audiences          Overview           Materials          Resources           Future Directions




Possible Audiences:

Undergraduate Biology, especially Genetics and Evolution courses  


Brief Overview:

Spreadsheet that randomly mutates nucleotide sequences and can model natural selective forces on the resulting proteins.  


Project Materials:

Spreadsheet: 97 and 2007 Excel versions Documentation pdf  


Resources and References:

Tony Weisstein, amino acid sequence from EvolSeq