This project was prepared as part of a BioQUEST faculty development workshop entitled ASM/BioQUEST Bioinformatics Institute at American Society for Microbiology in March 2007. The BioQUEST Curriculum Consortium is committed to the reform of undergraduate biology instruction through an emphasis on engaging students in realistic scientific practices. This approach is sometimes characterized as an inquiry driven approach and is captured in BioQUEST's three P's (problem-posing, problem-solving, and peer-persuasion). As part of this workshop groups of faculty were encouraged to initiate innovative curricular projects. We are sharing these works in progress in the hope that they will stimulate further exploration, collaboration and development. Please see the following links for additional information:

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Bioinformatic modules for Biology instruction
Authors          Audiences          Overview           Materials          Resources           Future Directions



Kelynne Reed
Austin College

Bradley Stevenson
University of Oklahoma

Jean Shingle
Immaculata University


Possible Audiences:

Freshman Biology to Upper level Molecular Biology  


Brief Overview:

Students will receive microbial DNA or protein sequence of unknown origin (to them).They will use various databases to investigate the gene identity, gene function, context (operon ?), phylogeny, genome structure and gene expression. Students will engage in both individual and collaborative learning by combining their indivdual findings and presenting as a group. These modules can be used indivdually or in combination to fit into any course regardless of time and population.  


Project Materials:

The Biology workbench The NCBI search site The Joint Genome Initiative Intergrated Microbial Genome database KEGG pathway database  


Future Directions:

Develop a problem space contain relevant data.  



- Gene neighborhood.doc
- trpA tryptophan synthase seq.txt
- Prjct21.ppt
- tryptophan synthaseA DNA1.txt