This project was prepared as part of a BioQUEST faculty development workshop entitled ASM/BioQUEST Bioinformatics Institute at American Society for Microbiology in March 2006. The BioQUEST Curriculum Consortium is committed to the reform of undergraduate biology instruction through an emphasis on engaging students in realistic scientific practices. This approach is sometimes characterized as an inquiry driven approach and is captured in BioQUEST's three P's (problem-posing, problem-solving, and peer-persuasion). As part of this workshop groups of faculty were encouraged to initiate innovative curricular projects. We are sharing these works in progress in the hope that they will stimulate further exploration, collaboration and development. Please see the following links for additional information:

Upcoming events               BEDROCK Problem Spaces

Poster: The Puzzling Properties of the Permease (PPP)
Authors          Audiences          Overview           Materials          Resources           Future Directions



Jennifer Galovich
College of Saint Benedict Saint John's University

Dave Westenberg
University of Missouri - Rolla

Ruth A. Gyure
Western Connecticut State University

Kim Finer
Kent State University


Possible Audiences:

Undergraduate biology majors  


Brief Overview:

We ask "Is there an E. coli - type iron permease gene (FepD) in Chromohalobacter sp. If so, is the perplasmic-facing residue sequence significantly different?  


Project Materials:

Web resources: JGI, NCBI, Biology Workbench. Also, BioQUEST ESTEEM module on protein analysis  


Resources and References:

(See references on slides.)  


Future Directions:

1. What might account for our conclusions? 2.Would we get different results if we looked at differences between transmembrane pI and periplasmic pI, instead of just the periplasmic pI values?  



- PPP revised DW.ppt