This project was prepared as part of a BioQUEST faculty development workshop entitled Bioinformatics Education Dissemination: Reaching Out, Connecting, and Knitting-together at University of Texas at Austin in May 2005. The BioQUEST Curriculum Consortium is committed to the reform of undergraduate biology instruction through an emphasis on engaging students in realistic scientific practices. This approach is sometimes characterized as an inquiry driven approach and is captured in BioQUEST's three P's (problem-posing, problem-solving, and peer-persuasion). As part of this workshop groups of faculty were encouraged to initiate innovative curricular projects. We are sharing these works in progress in the hope that they will stimulate further exploration, collaboration and development. Please see the following links for additional information:

Upcoming events               BEDROCK Problem Spaces

Creating a New Workspace: Genetic Diversity of Mycobacterium tuberculosis
Authors          Audiences          Overview           Materials          Resources           Future Directions



Diana Katz Amburn
Rogers State University

Robert Ketcham
University of Delaware


Possible Audiences:

courses in: General Biology Microbiology Immunology Genetics Molecular Genetics Epidemiology  


Brief Overview:

Tuberculosis infections have traditionally been considered to be due to infection with one strain (monoclonal). Researchers before the age of molecular biology found evidence for multiple strains and this is supported by a body of recent work which documents that many infections with Mycobacterium tuberculosis are polyclonal in origin. The tuberculosis organism is very efficient at becoming antibiotic resistant, and this workspace will examine these issues.  


Resources and References:

bibliography to be completed  



- Mtb_presentation.ppt
- Mtb_presentation1.ppt