This project was prepared as part of a BioQUEST faculty development workshop entitled Bioinformatics Education Dissemination: Reaching Out, Connecting, and Knitting-together at University of Texas at Austin in May 2005. The BioQUEST Curriculum Consortium is committed to the reform of undergraduate biology instruction through an emphasis on engaging students in realistic scientific practices. This approach is sometimes characterized as an inquiry driven approach and is captured in BioQUEST's three P's (problem-posing, problem-solving, and peer-persuasion). As part of this workshop groups of faculty were encouraged to initiate innovative curricular projects. We are sharing these works in progress in the hope that they will stimulate further exploration, collaboration and development. Please see the following links for additional information:

Upcoming events               BEDROCK Problem Spaces

Possible Audiences:

Undergraduate General Biology, Cell Biology, Biochemistry  

Project Materials:

Data base file of amino acid sequences for phosphofructokinase for selected organisms  

Future Directions:

Include more organisms in the study. Use amino acid sequence alignment to examine protein structure at a three dimensional level (Protein Explorer). Examine the evolution of active sites and allosteric regulatory sites of phosphofructokinase Establish evolutionary connections by phylogenetic analyses.