This project was prepared as part of a BioQUEST faculty development workshop entitled Bioinformatics Education Dissemination: Reaching Out, Connecting, and Knitting-together at University of Texas at Austin in May 2005. The BioQUEST Curriculum Consortium is committed to the reform of undergraduate biology instruction through an emphasis on engaging students in realistic scientific practices. This approach is sometimes characterized as an inquiry driven approach and is captured in BioQUEST's three P's (problem-posing, problem-solving, and peer-persuasion). As part of this workshop groups of faculty were encouraged to initiate innovative curricular projects. We are sharing these works in progress in the hope that they will stimulate further exploration, collaboration and development. Please see the following links for additional information:

Upcoming events               BEDROCK Problem Spaces

Antigenic shift v. drift in avian and mammalian Sino-influenza type A viruses.
Authors          Audiences          Overview           Materials          Resources           Future Directions



Charles Hauser
St. Edward's University

Mark Maloney
Spelman College

Michael Saclolo
St. Edward's University

Young Kim
Northland College


Possible Audiences:

Undergraduate Science Students and Instructors  


Brief Overview:

Each year the world community is concerned with potential effects of a new strain of influenza virus. Studying the evolution of such strains has become an essential tool with regard to synthesizing the appropriate vaccine to be distributed worldwide. This module aims to examine relationships between avian and mammalian strains, and the potential evolution of novel human strains. This exercise familiarizes students with the role of viral hemagglutinin diversity in pathology. The creation of new viral strains also challenges students' traditional view of evolution, antigenic drift, versus the mixing of viral genes that occurs during antigenic shift.  


Project Materials:

ClustalW NCBI Entrez  



- cmym11.ppt
- cmym1.ppt