This project was prepared as part of a BioQUEST faculty development workshop entitled Mammalian Bioinformatics at Jackson Laboratory in November 2004. The BioQUEST Curriculum Consortium is committed to the reform of undergraduate biology instruction through an emphasis on engaging students in realistic scientific practices. This approach is sometimes characterized as an inquiry driven approach and is captured in BioQUEST's three P's (problem-posing, problem-solving, and peer-persuasion). As part of this workshop groups of faculty were encouraged to initiate innovative curricular projects. We are sharing these works in progress in the hope that they will stimulate further exploration, collaboration and development. Please see the following links for additional information:

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Transferrins "R US! : An evolutionary look at changes in the structure of this protein
Authors          Audiences          Overview           Materials          Resources           Future Directions



Sarah Prescott
University of New Hampshire

Luci Levesque
Capital Area Technical Center

Emma Creaser
Unity College


Possible Audiences:



Brief Overview:

Our main question was what are the evolutionary relationships among various species using the transferrin protein as a model. A second focus was on answering the question of how much of the transferrin molecule is conserved among various species.  


Project Materials:

Transferrins Page A Project BEDROCK exploration site managed by Lisa Lambert. The ConSurf Server Server for identification of functional regions in proteins.  


Future Directions:

Come to the University of Vermont and actually play with the protein (and the hissing cockroaches!)!  



- transferrin.ppt