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Exploring Cancer Incidence Rates: Creating the Multi-hit Model of Cancer in STELLA.
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Non-science students, biology students (introductory, bioinformatics, cell biology, genetics), math students (math modeling). |
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Random mutations of nucleotides in genes during cell division can lead to cancer. Given a criterion for the onset of cancer we can create data for the length of time needed to produce cancer. This can lead to a frequency distribution of cancer cases as a function of age. |
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There are three different models constructed in STELLA included here. To run the models you will require STELLA8. You can download a demo version for free from http://www.hps-inc.com/ If you are using a Mac then you will have to convert the models after you have downloaded them. There is a PC Model Conversion Utility in the Tools folder of the STELLA8 demo. |
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