SCOPE Workshop, March 19-22, 2008 at the San Diego Supercomputing Center SCOPE Workshop, March 19-22, 2008 at the San Diego Supercomputing Center
        BioQUEST Curriculum Consortium
SCOPE: Science OnLine San Diego Supercomputer Center National Science Foundation
  
 
RAGIN' Leptin: A problem space on factors involved in energy homeostasis
 
 
Authors          Audiences          Overview           Materials          Resources           Future Directions
 

 


Authors


Stephen Everse
University of Vermont


Sarah Prescott Kenick
University of New Hampshire


Denise Robledo
Texas A&M University

 
   
 


Possible Audiences:

Undergraduates in General Biology, Biochemistry, Bioinformatics courses  

 
 


Brief Overview:

A problem space that provides an overview of genes and proteins that have connected roles in maintaining energy homeostasis. General diagram of energy homeostasis  

 
   
 


Project Materials:

See attachments HHMI video - The Science of Fat - provided a nice overview of the connections between leptin and obesity. http://www.hhmi.org/biointeractive/obesity/index.html Jackson Lab mouse informatics http://www.informatics.jax.org/  

 
 


Resources and References:

http://www.nutritionandmetabolism.com/content/3/1/40/abstract http://www.medscape.com/viewarticle/419086 http://www.ebmonline.org/cgi/content/full/228/10/1175  

 
   
 


Future Directions:

Progress on designing this problem space, including development of curricular resources  

 
 


Attachments


- adiponectin.fasta
- adrenergic_beta_3_receptor.fasta
- gastric_inhibitory_polypeptide.fasta
- ghrelin_sequences.fasta
- Leptin_sequences.fasta
- neuropeptide_y.fasta
- resistin.fasta
- EH_Structures.doc
- diagram.jpg
- energyhomeostatsisobesityandeatindisordersrecentadvancesinendocrinology.pdf
- Food_fails_to_suppress_ghrelin_levels_in_obese_humans.pdf
- ghrelinconceandenergybalance.pdf
- ghrelinthelinkbetweenenergyhomeostatsis.pdf
- howmanyaminoacidsinghrelininhibitsleptinandactivationinducedetc.pdf
- isenergyhomeostasissysteminherentlybiasedtowardweightgain.pdf
- obesity_and_insulin_resistance.pdf
- resistinandobesityassociatedinsulinresistance.pdf
- resistinlevelsandobesityorinsulinresitance.pdf
- A_war_on_obesity.pdf