IGERT NIMBIOS NSF
 
The Crash!!!!! HIV-The Silent Killer
 
 
Authors          Audiences          Overview           Materials          Resources           Future Directions
 

 


Authors


Arlin Toro
Universidad Interamericana de Puerto Rico

Alexandrine Randriamahefa
Oakwood University


Sanjukta Hota
Fisk University,Nashville

 
   
 


Possible Audiences:

Undergraduate Science majors  

 
 


Brief Overview:

Markham et al. on HIV evolution dataset within 15 individual patients is used in this study. Using this data we looked into the correlation between the mutation on the gp120 protein and the CD4 count decline.  

 
   
 


Project Materials:

- Markham data sets - Biology WorkBench - PDB - SwiSS-PDB Viewer  

 
 


Resources and References:

Biology Workbench (http://workbench.sdc.edu http://bioquest.org/micbescount MARKHAM.R.B, WEI-CINN WANG*, ANTON E. WEISSTEIN§, ZHE WANG*, ALVARO MUNOZ¶, ALAN TEMPLETON§, JOSEPH MARGOLICK*, DAVID VLAHOV¶, THOMAS QUINN\, HOMAYOON FARZADEGAN¶, AND XIAO-FANG YU(1998). Patterns of HIV-1 evolution in individuals with differing rates of CD4 T cell decline. Proc.Natl.Acad. Sci. 95(21):12568-73  

 
   
 


Attachments


- Crash.pptx