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Signal transduction molecules
 
 
Authors          Audiences          Overview           Materials          Resources           Future Directions
 

 


Authors


Peter Halbrooks
UVM


Peter Wilkinson
McGill


Peter Woodruff
Champlain College St-Lambert


Douglas Welsh
Princeton

 
   
 


Possible Audiences:

Molecular bilogists, biochemists, bioinformaticians  

 
 


Brief Overview

We are interested in molecules that are involved in signal transduction pathways; two-component signal transduction system. Several molecules are found to have sequence similarity. Transcriptional regulatory domains is almost always found associated with the response regulator receiver domain.  

 
   
 


Project Materials

NCBI protein databank, NCBI domains databank, PDB, BLOCKS Genedoc, Biology workbench, MEME  

 
 


Resources and References

 

 
   
 


Future Directions

look at evolutionary relationships specifically to the functional domains. Characterise the homology of CHEY in different species and elucidate the structural/functional relationships.  

 
 


Attachments


- AToC_20Chey-like_20receivers.txt
- CheYalign.PDF
- AToC_Alignment_with_Blocks_result.msf