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Illustrating Conserved Residues on 3D Molecules: Lactoferrins
 
 
Authors          Audiences          Overview           Materials          Resources           Future Directions
 

 


Authors


Lisa Lambert
Chatham College


Holly Perri
Chatham College




 
   
 


Possible Audiences:

Genetics, biochemistry, molecular biology, bioinformatics classes  

 
 


Brief Overview

We were interested in knowing which amino acids are conserved in lactoferrins but NOT in other mammalian serum proteins. We did sequence alignments of the serum and lactoferrins, compared them, then used Protein Explorer and Paint to illustrate our results. Highlighted are some of the residues conserved in all eight lactoferrins but showing variability in the analogous serum transferrin sites. A protocol is included  

 
   
 


Project Materials

Sequences from Transferrin website  

 
 


Resources and References

Biology Workbench; Protein Explorer; Transferrin web site  

 
   
 


Future Directions

Compare other conserved sequences between transferrin paralogs.  

 
 


Attachments


- project.doc