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Introductory Bioinformatics Problem Set:
Creating Scenarios to Introduce Students to Types of Bioinformatics Tools


Authors          Audiences         Project           Materials          Resources           Future Directions



Shalini Prasad
Shary Rosenbaum
East Bay Biotechnology
Education Program
Octavio Rodriguez
Gene Connection/BABEC



Possible Audiences:

9-10 Grade Life Science Students





    1. Sequence Alignment
    2. Pattern Match
    3. Identity Match
    4. Tree Building (distance based trees, character based trees)
    5. Structure Analysis

2-Looking for Huntington's Disease (looking for repeatable elements).
3-Down Syndrome (pre-natal)
3-Forensic Identification (DNA matching)
3-Paternity Cases
4-Zoo Management (tiger population in third generation, does it need a new sperm donor to ensure to select a sperm donor)
4-Conservation (Chris Branneger [sp?] redwood - which isolated populations are the most important to preserve)(Whale in foods..)
4-Dentist infected his patients with HIV? Using tree to develop
2-What type of DNA patterns are found in genes rich genome areas? (localizing target areas)
5-Hemoglobin for Sickle Cell and Beta Thalassemia.
1-Finding a protein in an animal and looking for similar protein in humans. (researcher thinks s/he has ID a new gene, but want to determine if someone has already ID'd it in any organism.) (Finding a substitute protein in other organisms for human needs- insulin)
What proteins are exclusively expressed in Cancer?
Which proteins are modified in Cancer cells?


Project Materials

Internet Access
Selected Introductory Case Study Materials



Resources and References

Relevant text materials and some problem sets will be simulated.


Future Directions

Will develop introductory lesson to go along with these case studies. Will also develop an IMMEX introductory problem set.