This project was prepared as part of a BioQUEST faculty development workshop entitled Annual BioQUEST Faculty Summer Workshop
Global Health in Undergraduate Education at Beloit College in June 2010. The BioQUEST Curriculum Consortium is committed to the reform of undergraduate biology instruction through an emphasis on engaging students in realistic scientific practices. This approach is sometimes characterized as an inquiry driven approach and is captured in BioQUEST's three P's (problem-posing, problem-solving, and peer-persuasion). As part of this workshop groups of faculty were encouraged to initiate innovative curricular projects. We are sharing these works in progress in the hope that they will stimulate further exploration, collaboration and development. Please see the following links for additional information:

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Hormones, Drugs, and Pregnancy
  
 
Authors          Audiences          Overview           Materials          Resources           Future Directions
  

 


Authors

  
 
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Possible Audiences:

College; High School Upperclassmen  

 
 


Brief Overview:

Problem based learning approach to study of hormones, birth control and pregnancy. Incorporates analysis of female reproductive cycle, pharmacokinetics and cell signaling. Appropriate for A&P, cell biology and pharmacology courses.  

 
 
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Project Materials:

Teacher's guide for Module (powerpoint and word documents) Female Reproductive Cycle ESTEEM Module Female Reproductive animation (http://www.healcentral.org/content/collections/McGill/MENSESANIMFINAL800x600.swf) Two Compartment Pharmacokinetics ESTEEM Module - Longer Timescale One Compartment Pharmacokinetics ESTEEM Module - Longer Timescale Two Compartment Pharmacokinetics ESTEEM Module - Two Weeks One Compartment Pharmacokinetics ESTEEM Module - Two Weeks Product information labels for Aygestin and Depo-provera Steroid hormone powerpoint (http://www.the-aps.org/education/refresher/Wierman%20talk/player.html)  

 
 


Resources and References:

1. Aygestin® Product Insert, Duramed Pharm., Inc., Pomona, NY, July 2007 2. Drugs@FDA, http://www.accessdata.fda.gov/scripts/cder/drugsatfda/ 3. Conneely, O. and B. Jericevic. Progesterone Regulation of Reproductive Function Through Functionally Distinct Progesterone Receptor Isoforms. Rev. in Endocrine & Metabolic Disorders 3:201, 2002 4. Menstrual cycle hormone animation, IAMSE http://www.healcentral.org/content/collections/McGill/MENSESANIMFINAL800x600.swf 5. Physician Information for Depo-Provera Pharmacia & Upjohn Company, Kalamazoo, MI, Feb. 2004 6. Shughrue, P., D. Lubahn, A. Negro-Vilar, K. Korach, and I. Merchenthaler. Responses in the brain of estrogen receptor a-disrupted mice. PNAS, 94:11008, 1997 7. Spitznagel, E. (Fall 1992) Two-Compartment Pharmacokinetic Models C-ODE-E. Harvey Mudd College, Claremont, CA. 8. Wierman, M. Sex steroid effects at target tissues: mechanisms of action, Advan. Physiol. Edu. 31: 26-33, 2007 9. Wierman, M. http://www.the-aps.org/education/refresher/Wierman%20talk/player.html 10. Yeargers, E.K., Shonkwiler, R.W., and Herod, J.V. (1996) An Introduction to the Mathematics of Biology. Birkhäuser.  

 
 
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Future Directions:

1. Elaborate and improve Hormone Module 2. Public health applications using GapMinder & CDC Website 3. Pharmacokinetics Modules (Documentation, Case Study, Sample Labs) 4. Model for cell signaling mechanisms using AgentSheets