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The FtsH Proteases of Oryza sativa and Arabidopsis thaliana – Orthologs and Parologs?
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Biology undergraduates |
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Arabidopsis thaliana is a dicot for which a complete genome sequence is available. The plant seems to have an unusually large number of genes coding for proteolytic enzymes. These genes belong to a few multi-gene families. Among these is the multi-gene family representing the FtsH proteases, typified by the presence of an ATP-binding domain and energy requirement coming from ATP hydrolysis. Oryza sativa (rice) is a monocot for which a complete genome sequence has only recently been completed. The presence of such information allows us to ask the question: Did the multiple FtsH proteases of Arabidopsis thaliana arise before or after divergence of the monocots and dicots? |
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Poster, as MS-Word .doc file, attached |
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Sakamoto W, Tamura T, Hanba-Tomita Y, Murata M; Sodmergen. The VAR1 locus of Arabidopsis encodes a chloroplastic FtsH and is responsible for leaf variegation in the mutant alleles. Genes Cells. 2002 Aug;7(8):769-80. Bailey S, Thompson E, Nixon PJ, Horton P, Mullineaux CW, Robinson C, Mann NH. A critical role for the Var2 FtsH homologue of Arabidopsis thaliana in the photosystem II repair cycle in vivo. J Biol Chem. 2002 Jan 18;277(3):2006-11. Epub 2001 Nov 20. Bailey S, Silva P, Nixon P, Mullineaux C, Robinson C, Mann N. Auxiliary functions in photosynthesis: the role of the FtsH protease. Biochem Soc Trans. 2001 Aug;29(Pt 4):455-9. Lindahl M, Spetea C, Hundal T, Oppenheim AB, Adam Z, Andersson B. The thylakoid FtsH protease plays a role in the light-induced turnover of the photosystem II D1 protein. Plant Cell. 2000 Mar;12(3):419-31. |
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