This project was prepared as part of a BioQUEST faculty development workshop entitled ASM/BioQUEST Bioinformatics Institute at American Society for Microbiology in March 2007. The BioQUEST Curriculum Consortium is committed to the reform of undergraduate biology instruction through an emphasis on engaging students in realistic scientific practices. This approach is sometimes characterized as an inquiry driven approach and is captured in BioQUEST's three P's (problem-posing, problem-solving, and peer-persuasion). As part of this workshop groups of faculty were encouraged to initiate innovative curricular projects. We are sharing these works in progress in the hope that they will stimulate further exploration, collaboration and development. Please see the following links for additional information:

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Re-annotation of nitrate reductase gene cluster
Authors          Audiences          Overview           Materials          Resources           Future Directions



Cristina Iftode
Rowan University

Toby Mapes
Asheville-Buncombe Technical Community College

Zhaohui Xu
Bowling Green State University

Qiang He
University of Tennessee- Knoxville


Possible Audiences:

Class peers  


Brief Overview:

Desulfovibrio vulgaris is a sulfate reducing bacterium. Its genome has a complete nitrate reductase according to the current annotation; however, nitrate can neither be used as a terminal electron acceptor nor as nitrogen source. Even though the organism has a confirmed nitrite reductase no biochemical evidence has been found to support the presence of the annotated nitrate reductase.  



- bioquest11.ppt