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Do HIV+ Rapid Progressors Show More Divergenece than Non-Progressors?
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Other bioinformatics workshop participants |
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Analysis of HIV env sequence data from Bedrock dataset to test the hypothesis that the viral population of rapid progressors to AIDS may be more complex than that of non-progressors. |
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HIV env nucleotide sequences from patient virus samples collected at 6 month intervals during clinic visits over a period of 3 to 6 years |
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(1) Markham, R.B. et al. (1998) P.N.A.S. USA 95:12568, source of our dataset and the source of the genome map used in the poster. (2) "Evolutionary Bioinformatics: Microbial analyses from sequence to structure to function to ecology", ASM March 2-5, 2006 workshop materials, including the Markham paper et al with dataset in print form and the dataset in silico, and awsome instructors. (3) Sequence analysis tools provided by the Biology Workbench http://workbench.sdsc.edu. |
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Were ruminating on how to make a quantitative analysis of whether the distance matrices generated by the multiple sequence alignments track with differences in T-cell counts among the progressors & non-progressors in our dataset. |
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