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This project was prepared as part of a BioQUEST faculty
development workshop entitled Bioinformatics in Biology Education: Working with Sequence, Structure and Function at
Oklahoma City Community College in
January 2005. The BioQUEST Curriculum Consortium is committed to the reform of undergraduate biology
instruction through an emphasis on engaging students in
realistic scientific practices. This approach is sometimes
characterized as an inquiry driven approach and is
captured in BioQUEST's three P's (problem-posing,
problem-solving, and peer-persuasion). As part of this workshop groups of faculty
were encouraged to initiate innovative curricular
projects. We are sharing these works in progress in the
hope that they will stimulate further exploration,
collaboration and development.
Please see the following links for additional information:
Upcoming events BEDROCK Problem Spaces
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Undergraduate Biology Majors
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Understand the relationships between DNA, RNA, and proteins.
Explore the effects of tertiary protein structural changes on enzyme function.
Learn to utilize tools available in bioinformatics
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Primary Literature
Protein Explorer
Biology Workshop
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Article: Rupp, J. et. al., Serine to asparagine
substitution in the gyrase A gene leads to
quinolone resistance in moxifloxacin-exposed
Chlamydia pneumoniae.
Website: www.ncbi.nlm.nih.gov
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This initial exercise is used to introduce the problem space and tools available.
Students are then assigned a specific antibiotic resistance model to explore mutations and protein tertiary structure changes that result from these mutations.
Students then present results in a professional format.
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- BrendaNancyWesFinal.ppt
- dam1.gif
- dam_loggers2.gif
- dam3.gif
- dam4.gif
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