Axon is a simulation of the classic Hodgkin-Huxley (1952) model for axon
excitation formulated from their voltage clamp measurements upon the squid
axon. It provides you with a simulated excised peripheral nerve from a
squid and allows you to perform experiments by setting the environment
of the axon, applying stimuli or clamps, and generating one or more action
potentials. Using the tools in Axon, you can create experiments which
explore a variety of nerve properties, such as threshold, refractory period,
accommodation, and summation.
Axon also has a problem editing utility that allows you to customize
a problem to meet your specific needs. You can edit an existing problem
or create an entirely new one. Using this utility you can change the characteristics
of the experiment parameters to simulate a particular model, create simple
or complex problems by hiding/showing parameters, and customize the appearance
of the data table and the Summary Window.
Associated with each Axon experiment is an Experiment Summary
window, shown above. The figure above illustrates the Summary
Window for a problem which was created with everything enabled.
Using the tools in this window you will set up the experiment
parameters, run one or more experimental trials, and display the
The figure above shows the Experiment Summary window after
three runs with different stimulus durations. The current trial
(Trial 3) is drawn in black. The Membrane Cartoon, drawn under
the data table, represents a cross-section of the cell wall of
the axon, showing the outside of the cell, the inside of the cell,
and the axon plasma membrane.
- System 6.07 or later; System 7.1 or later for Power Macintosh.
- At least 800K of available RAM, more for complex simulations.