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8:15 – 8:25 AM |
Registration in Room 337, McPheeter–Dennis Hall |
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8:30 – 8:40 AM |
Welcome by Dr. Webb and Dr. Finkelstein of CAU |
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8:40 – 9:15 AM |
Program Introduction
John R. Jungck
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9:15 – 9:45 AM
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HIV in Evolution
Sam Donovan |
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10 AM – Noon |
Bioinformatics Problem Solving Session #1 Exploring
HIV change within and between patients: Drawing biologically meaningful
inferences from molecular data – forensics cases.
Sam Donovan and
Tony Weisstein |
Noon – 1:15 PM |
Lunch |
1:15 – 2:30 PM |
Toward a Theoretical
Basis for Bioinformatics: Genetic Codes as Codes
John R. Jungck
Bioinformatics has largely been developed upon an empirical basis
of statistical patterns; I believe that coding and information theoretical
perspectives along with evolution and biophysics may help us develop
a more theoretically grounded bioinformatics. Mathematical properties
of genetic codes will be demonstrated with respect to their efficiencies,
rates of transmission, detectability and correctability and of errors,
symmetries, and origins by employing coding theory (Baudot codes,
Gray codes, Hamming codes, Huffman Codes (Fractals and Power Laws),
comma free codes, etc.), algorithmic complexity, abstract algebra,
graph theory, combinatorics, information theory, and phylogenetic
systematics of sequences. Genetic codes become much more understandable
and elegant to biologists when they are not considered as mere ciphers,
but are instead understood from three perspectives: codes per se,
physical chemical interactions, and evolutionary selective pressures.
In addition, I will illustrate some of the alternative distance metrics
based upon different mathematical representations of genetic codes
which have utility in genomic data base searching (comparative sequence
analyses) and considerations of different evolutionary mechanisms.
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2:30 – 3:30 PM |
Problem
Solving Session #2
Chimpanzee Conservation Genetics
Sam Donovan |
3:30 – 4:30 PM |
Group work |
4:30 PM |
Social hour |
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8:30 – 9:30 AM |
Participant presentations |
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9:30 – 11:00 AM
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Problem Solving Session #3
Protein Explorer with Enolase. Tia Johnson and Sam
Donovan
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11:00 – Noon |
Problem Solving Session #4
Phylogenetic Trees: An introduction to understanding and teaching
phylogenetic concepts and methods
Tony
Weisstein |
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Noon – 1:15 |
Lunch |
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1:15 – 2:30 PM |
Multiple Sequence Alignment & Accelrys' GCG
Wisconsin Package
Steven
Thompson, School of Computational
Science and Information Technology (CSIT), Florida State University,
Tallahassee, Florida
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2:45 – 3:45 PM |
Problem Solving Session #5
Tree of Life: Exploring evolutionary relationships between
bacteria using online sequence data from GenBank.
Sam Donovan, Tony Weisstein, Steve Thompson, Tia Johnson |
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3:45– 4:00 PM
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Break |
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4:00 – 5:30 PM |
Group work |
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8:30 – 9:15 AM
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Finish up
group projects |
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9:15 – 10:30 AM |
Project presentations |
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10:30 – Noon
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Overview of BioQUEST Curriculum Consortium – BEDROCK
(Bioinformatics Education Dissemination: Reaching Out, Connecting
and Knitting–together)
Sharing information about personal projects
and courses; how to contribute and stay involved; distribute additional
papers and CDs; feedback and wrap–up
John R. Jungck, Tia Johnson, Sam Donovan, Tony Weisstein
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Noon |
Evaluation forms & new course suggestions |
For more
information please contact Sam Donovan
or Sue Risseeuw (608/363–2012).
Sponsored
by a grant from the National Science Foundation (DUE/CCLI-ND),
the BioQUEST Curriculum Consortium and
hosted by
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